António Soure

Ph.D. Student (M.I.T. Portugal Program)


Research Activities

I am interested in the GMP-compliant isolation and expansion of mesenchymal stem cells (MSC). Due to the potential hurdles of using fetal bovine serum as supplement of MSC culture media, the scientific community is looking for alternatives in this regard. Chemically defined xeno-free culture media are now being commercialized but their exact composition is not fully disclosed. Human platelet lysate arises as a potential candidate in solving this issue.

 

Selected publications

 

Andrade, P. Z., de Soure, A.M., dos Santos, F., Paiva, A., Cabral, J.M.S., da Silva, C.L. (2013) “Ex vivo expansion of cord blood haematopoietic stem/progenitor cells under physiological oxygen tensions: clear-cut effects on cell proliferation, differentiation and metabolism.” Journal of Tissue Engineering and Regenerative Medicine DOI: 10.1002/term.1731

 

 

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